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Isaiah Kletenik, MD

Isaiah Kletenik, MD

Investigator

Assistant Professor of Neurology, Harvard Medical School · Behavioral Neurologist, Brigham and Women's Hospital

Isaiah Kletenik is an Assistant Professor of Neurology at Harvard Medical School and a Behavioral Neurologist at Brigham and Women’s Hospital. He earned an MD from the University of Washington and completed residency in Neurology and Fellowship in Behavioral Neurology & Neuropsychiatry at the University of Colorado.

He is a neuroimaging researcher in the Center for Brain Circuit Therapeutics, employing functional and structural brain connectivity to better understand alterations in cognitive function and subjective experience.

Selected publications

  1. Lesion network mapping of focal injury-related aggression finds two distinct network injury patterns

    Miller GN , Lu Z , Peng S , Kletenik I , Ortega-Márquez J , Tripathy S , Wall J , Darby RR , Cohen AL

    Brain Communications · 2026

    Gillian Miller, BA Gillian Miller Zexia Lu, MS, BA Zexia Lu Shaoling Peng, PhD Shaoling Peng Isaiah Kletenik, MD Isaiah Kletenik Jorge Ortega Marquez, MD, MMSc Jorge Ortega Marquez Shreya Tripathy, BA Shreya Tripathy Juliana Wall Juliana Wall Alexander Li Cohen, MD, PhD Alexander Li Cohen
    Mentee-led Cohen first/senior Open access DOI Scholar

  2. Lesions causing aphantasia are connected to the fusiform imagery node

    Kutsche J , Howard C , Palacin AC , Drew W , Michel M , Cohen AL , Fox MD , Kletenik I

    Cortex · 2026

    Alberto Castro Palacin, BS, MSc Alberto Castro Palacin Alexander Li Cohen, MD, PhD Alexander Li Cohen Isaiah Kletenik, MD Isaiah Kletenik
    Cited by 4 Collaboration DOI Scholar

  3. Mapping Lesions That Cause Psychosis to a Human Brain Circuit and Proposed Stimulation Target

    Pines AR , Frandsen SB , Drew W , Meyer GM , Howard C , Palm ST , Schaper FLWVJ , Lin C , Butenko K , Ferguson M , Friedrich MU , Grafman JH , Kappel AD , Neudorfer C , Rost NS , Sanderson LL , Taylor JJ , Wu O , Kletenik I , Vogel JW , Cohen AL , Horn A , Fox MD , Silbersweig D , Siddiqi SH

    JAMA Psychiatry · 2025

    Isaiah Kletenik, MD Isaiah Kletenik Alexander Li Cohen, MD, PhD Alexander Li Cohen
    Cited by 28 Collaboration Open access DOI Scholar

  4. Mapping Neuroimaging Findings of Creativity and Brain Disease Onto a Common Brain Circuit

    Kutsche J , Taylor JJ , Erkkinen MG , Akkad H , Khosravani S , Drew W , Abraham A , Ott DVM , Wall J , Cohen AL , Horn A , Neumann WJ , Kletenik I , Fox MD

    JAMA Network Open · 2025

    Juliana Wall Juliana Wall Alexander Li Cohen, MD, PhD Alexander Li Cohen Isaiah Kletenik, MD Isaiah Kletenik
    Cited by 19 Collaboration Open access DOI Scholar

  5. White matter disconnection in acquired criminality

    Kletenik I , Filley CM , Cohen AL , Drew W , Churchland PS , Darby RR , Fox MD

    Molecular Psychiatry · 2025

    Isaiah Kletenik, MD Isaiah Kletenik Alexander Li Cohen, MD, PhD Alexander Li Cohen
    Cited by 8 Mentee-led Collaboration Open access DOI Scholar

  6. Multiple sclerosis lesions that impair memory map to a connected memory circuit

    Kletenik I , Cohen AL , Glanz BI , Ferguson M , Tauhid S , Li J , Drew W , Polgar-Turcsanyi M , Palotai M , Siddiqi SH , Marshall GA , Chitnis T , Guttmann CRG , Bakshi R , Fox MD

    Journal of Neurology · 2023

    Isaiah Kletenik, MD Isaiah Kletenik Alexander Li Cohen, MD, PhD Alexander Li Cohen
    Cited by 19 Mentee-led Collaboration Open access DOI Scholar

  7. Network Localization of Awareness in Visual and Motor Anosognosia

    Kletenik I , Gaudet K , Prasad S , Cohen AL * , Fox MD *

    Annals of Neurology · 2023

    Isaiah Kletenik, MD Isaiah Kletenik Alexander Li Cohen, MD, PhD Alexander Li Cohen
    Cited by 32 Mentee-led Cohen first/senior Collaboration Open access DOI Scholar

  8. Network Localization of Unconscious Visual Perception in Blindsight

    Kletenik I , Ferguson M , Bateman JR , Cohen AL , Lin C , Tetreault A , Pelak VS , Anderson CA , Prasad S , Darby RR , Fox MD

    Annals of Neurology · 2021

    Isaiah Kletenik, MD Isaiah Kletenik Alexander Li Cohen, MD, PhD Alexander Li Cohen
    Cited by 33 Mentee-led Collaboration DOI Scholar

* co-first / co-senior author